Scientists Discover Hormone Blocks Pot "High" - KMSP-TV

Scientists Discover Hormone Blocks Pot "High"

Posted: Updated:
 French researchers have discovered that a naturally occurring hormone acts as a defense in the brain against the psychoactive effects of marijuana consumption.

The hormone, pregnenolone reduces the activity of a brain molecule that acts as a cannabinoid receptor.
 
Researches think the discovery could help people with addictions to marijuana, as well as allowing people to take medical marijuana without the behavioral effects.
 
The study was published in the journal Science.
 
About 147 million people globally – or about 2.5 percent of the population – use cannabis, according to the World Health Organization.

While cannabis products can alleviate symptoms of depression, glaucoma, spasms, and nausea associated with cancer and AIDS, they are also known to impair brain development, memory and lung function, and some say they can lead to addiction.

Researchers discovered the previously unknown role of pregnenolone when they administered high doses of cannabis to lab rats, on the order of three to 10 times more than the typical human marijuana smoker might be exposed to, Piazza told AFP.

The high doses of cannabis raised the brain's level of pregnenolone, which blocked the harmful effects of THC on the brain.

They also did tests in the lab on human cell lines – not human patients – that showed a similar blocking effect.

"We hope to be able to start clinical trials in people in a year to a year and a half," Piazza told AFP.

  • Share ThisMore>>

  • myFOX Tech

    Early Preview: Microsoft Windows Phone's Cortana

    Early Preview: Microsoft Windows Phone's Cortana

    Wednesday, April 16 2014 12:34 PM EDT2014-04-16 16:34:11 GMT
    Move over Google Now and Siri, there's a new gal in town and she's pretty classy! I take an early look at Microsoft's new smartphone personal digital assistant, Cortana.
    Move over Google Now and Siri, there's a new gal in town and she's pretty classy! I take an early look at Microsoft's new smartphone personal digital assistant, Cortana.
  • myFOX Tech

    Tired, Sore Eyes? Enter: Gunnar Optiks Intercept

    Tired, Sore Eyes? Enter: Gunnar Optiks Intercept

    Tuesday, April 15 2014 11:22 AM EDT2014-04-15 15:22:42 GMT
    I met the folks from Gunnar Optiks at CES this year and they had something new to show me. The Intercepts. I have a big head, these are big frames, it was kismet but do they work as good as they look? We'll see.
    I met the folks from Gunnar Optiks at CES this year and they had something new to show me. The Intercepts. I have a big head, these are big frames, it was kismet but would my eyes revel in this serendipitous confluence of events? We'll see.
  • Sure, Cats Make Messes, But At Least Willie Cleans Up After Himself

    Sure, Cats Make Messes, But At least Willie Cleans Up After Himself

    Thursday, April 10 2014 12:05 AM EDT2014-04-10 04:05:18 GMT
    How about a little lesson on conservation from Willie the Cat. Willie starts unrolling all of the paper until it is all on the floor. But you have to watch what happens next in this viral video.
    How about a little lesson on conservation from Willie the Cat. Willie starts unrolling all of the paper until it is all on the floor. But you have to watch what happens next in this viral video.
  • Health NewsMore>>

  • Dr. Sonu Ahluwalia: Tamiflu For Symptoms, An App For Jet Lag?

    Dr. Sonu Ahluwalia: Tamiflu For Symptoms, An App For Jet Lag?

    Monday, April 14 2014 11:42 AM EDT2014-04-14 15:42:32 GMT
    There are medications such as Tamiflu to curb or reduce symptoms, but a new report from the British Medical Journal says there is no evidence to suggest it works.
    There are medications such as Tamiflu to curb or reduce symptoms, but a new report from the British Medical Journal says there is no evidence to suggest it works.
  • Implants May Hold Key to Weight Loss

    Implants May Hold Key to Weight Loss

    Monday, April 7 2014 8:05 PM EDT2014-04-08 00:05:19 GMT
    What if you didn't have to conjure up superhuman willpower to resist food temptations? What if you had the power to make the desire to overeat disappear? 
    What if you didn't have to conjure up superhuman willpower to resist food temptations? What if you had the power to make the desire to overeat disappear? 
  • Bikini Baristas Too Hot For Some

    Bikini Baristas Too Hot For Some

    Monday, April 7 2014 4:48 PM EDT2014-04-07 20:48:44 GMT
     Bikini-clad baristas who work at a Northern California coffee shop are brewing up a bit of controversy with some folks upset with their attire. 
     Bikini-clad baristas who work at a Northern California coffee shop are brewing up a bit of controversy with some folks upset with their attire. 
Powered by WorldNow

KMSP-TV
11358 Viking Drive
Eden Prairie, MN 55344

Phone: (952) 944-9999
Fax: (952) 942-0455

Didn't find what you were looking for?
All content © Copyright 2000 - 2014 Fox Television Stations, Inc. and Worldnow. All Rights Reserved.
Privacy Policy | Terms of Service | Ad Choices